PNL8 TRIPTANS IN THE ACUTE TREATMENT OF MIGRAINE: COSTEFFECTIVENESS ANALYSIS BASED ON NUMBER NEEDED TO TREAT AND DOSES NEEDED TO TREAT

Triptans for migraine therapy: a comparison based on number needed to treat and doses needed to treat.

OBJECTIVE Managed care and other decision makers need sound comparative information to support the formulary selection process and reimbursement decisions for the treatment of migraine. The objective of this study was to compare currently marketed triptan therapies using number-needed-to-treat (NNT) and doses-needed-to-treat (DNT) measures. DNT was further used to derive triptan treatment cost ...

Number Needed to Treat

Number needed to treat (NNT); number needed to harm (NNH).

Number needed to treat and baseline risks.

[Using "number needed to treat" to interpret treatment effect].

Evidence-based medicine (EBM) has rapidly emerged as a new paradigm in medicine worldwide. The clinical medicine in twenty-first century could be the era of EBM. Randomized controlled trial has been regarded as the gold standard for evaluating the treatment effect of a new drug or a new therapy. The effect of a treatment versus controls may be expressed in relative or absolute measures. Relativ...